Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection

Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection

Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis in infants and children worldwide. Many animal models are used to study RSV, but most studies investigate disease in adult animals which does not address the unique physiology and immunology that makes infants more susceptible. The perinatal (preterm and term) lamb is a useful model of infant RSV disease as lambs have...

Effects of Formalin-Inactivated Respiratory Syncytial Virus (FI-RSV) in the Perinatal Lamb Model of RSV

Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis in infants and children worldwide. There are currently no licensed vaccines or effective antivirals. The lack of a vaccine is partly due to increased caution following the aftermath of a failed clinical trial of a formalin-inactivated RSV vaccine (FI-RSV) conducted in the 1960's that led to enhanced disease, necessita...

Respiratory Syncytial Virus (RSV) Infection

Identification of Respiratory Syncytial Virus (RSV) Genome in the Stool of a Child with Acute Gastroenteritis

Case Report: Some viruses have been reported to cause respiratory and gastroenteric infections simultaneously. In this case we present isolation of human respiratory virus (RSV) type B from diarrheal sample of a 12 months' child with acute gastroenteritis. Results: The results indicated the presence of RSV subtype B genome in all three stool samples. Moreover, no sign of co-infections with oth...

What is respiratory syncytial virus (RSV)?

one of the most common causes of bronchiolitis and pneumonia in children under 1 year of age in the United States. It is a common reason for young infants to be hospitalized during the RSV season. RSV can also cause serious respiratory illness in older adults. Most healthy people recover from RSV infection in 1 to 2 weeks. However, infection can be severe in a few, usually among those who are a...